New Origin of Life Proposed: Zinc & Zap

By | September 4, 2009

New Origin of Life Proposed Zinc  Zap

The Miller-Urey experiment, conducted by chemists Stanley Miller and Harold Urey in 1953, is the classic experiment on the origin of life. It established that the early Earth atmosphere, as they pictured it, was capable of producing amino acids, the building blocks of life, from inorganic substances.

Now, more than 55 years later, two scientists are proposing a hypothesis that could add a new dimension to the debate on how life on Earth developed.

Armen Mulkidjanian of the University of Osnabrueck, Germany and Michael Galperin of the U.S. National Institutes of Health present their hypothesis and evidence in two papers published and open for review in the web site Biology Direct.

… Mulkidjanian’s “Zn world” hypothesis presents a different version of the prebiotic Earth atmosphere—one in which zinc sulfide plays a major role in the development of life. In nature, zinc sulfide particles precipitate only at deep-sea hydrothermal vents. Its unique ability to store the energy of light has made it popular in many modern-day devices, from various types of television displays to glow-in-the-dark items (and zinc oxide is used in sunscreen).

Its ability to store light makes zinc sulfide an important factor in the discussion on life’s origin. Mulkidjanian explains that, once illuminated by UV light, zinc sulfide can efficiently reduce carbon dioxide, just as plants do.

To test the hypothesis, Mulkidjanian and Galperin analyzed the metal content of modern cells and found “surprisingly high levels of zinc,” particularly in the complexes of proteins with DNA and RNA molecules.

“We have found that proteins that are considered ‘evolutionarily old’ and particularly those related to handling of RNA specifically contain large amounts of zinc,” Mulkidjanian says.

The scientists say the result is evidence that the first life forms evolved in a zinc-rich environment. But as the authors indicate in their paper, acceptance of a new hypothesis for the origin of life will likely require more work, particularly to further describe the nature of life and the chemical reactions in these zinc-rich communities.

“We cannot explain fully the properties of modern organisms unless we understand how life has originated,” says Mulkidjanian.

For astrobiologists, this new hypothesis presents a considerable shift in the debate on the origin of life.

“If this hypothesis is adopted in the origins of life community, it would represent a real conceptual shift, and so it would be significant,” says NASA astrobiologist Max Bernstein

via New Origin of Life Proposed: Zinc & Zap – Yahoo! News.

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