Nanotechnology has restored the sight of blind rodents, a new study shows. Scientists mimicked the effect of a traumatic brain injury by severing the optical nerve tract in hamsters, causing the animals to lose vision. After injecting the hamsters with a solution containing nanoparticles, the nerves re-grew and sight returned.
Nerve growth (shown in green) occurred after the injections. … Once inside the hamster’s brain, the peptides spontaneously arranged into a scaffold-like criss-cross of nanofibres, which bridged the gap between the severed nerves.
The scientists discovered that brain tissue in the hamsters knitted together across the molecular scaffold, while also preventing scar tissue from forming. Importantly, the newly formed brain tissue enabled the brain nerves to re-grow, restoring vision in the injured hamsters.
“We made a cut, put the material in, and then we looked at the brain over different time points,” explained Dr Rutledge Ellis-Behnke, a neuroscientist at MIT and lead author on the paper.
“The first thing we saw was that the brain had started to heal itself in the first 24 hours. We had never seen that before – so that was very surprising.” – BBC