My experience: Oravive with NovaMin

By | October 11, 2008

My experience Oravive with NovaMin

Comparison of NovaMin† and other Calcium Phosphate Technologies

NovaMin releases high levels of Ca2+ and P5+ into the oral environment, along with Na+ that increases oral pH, creating the ideal conditions for rapid tooth remineralization.

The silica containing Ca, PO and Na bind to the tooth surface.

The Na buffers the pH above 7 (the pH is needed to be above 7 to allow for the precipitation of crystals onto the tooth surface)

The NovaMin will release rapid and continuous deposition of a natural, crystalline hydroxyl-carbonate apatite (HCA) layer that is chemically and structurally the same as tooth mineral. No other man-made materials is known to directly lead to the formation of these crystals in the body. NovaMin has also been shown to have significant anti-microbial and anti-inflammatory benefits.

Clinically Proven Benefits

  • Significant reduction of tooth sensitivity.
  • Remineralization of acid erosion and abrasion.
  • Inhibiting the development of dental caries.
  • Significant reduction of gingivitis.
  • Consumer noticeable whitening.

NovaMin has no fluoride and it really heals teeth by regrowing them with actual tooth material. I purchased mine from Oravive.

It does have some stuff in it that I question. One is sodium lauryl sulfate, but they are working on a formula without that.

The ingredients of Oravive intensive mineral therapy dentifrice are: Glycerin (usually bad in toothpaste, but might be good in this case), PEG-8 distearate, Silica, Calcium sodium phosphosilicate (NovaMin), Sodium Lauryl sulfate, Titanium dioxide, Aroma, Carbomer (aka carbamide peroxide a bleaching agent), and Potassium acesulfame sweetener.

They instructions say to brush, and spit, but don’t rinse. Carbamide peroxide has some warnings, however, that were not included with the product. I’ll ask them about this when I get time.

Oral: With prolonged use of oral carbamide peroxide, there is a potential for overgrowth of opportunistic organisms; damage to periodontal tissues; delayed wound healing; should not be used for longer than 7 days; not for OTC use in children <2 years of age

Otic: Do not use if ear drainage or discharge, ear pain, irritation, or rash in ear; should not be used for longer than 4 days; not for OTC use in children <12 years of age – umm

Acesulfame Potassium (K) was approved for use by the FDA as a safe artificial sweetener in July, l988. It is a derivative of acetoacetic acid. Unfortunately, several potential problems associated with the use of acesulfame have been raised. They are based largely on animal studies since testing on humans remains limited.

The findings showed the following:
Acesulfame K stimulates insulin secretion in a dose dependent fashion thereby possibly aggravating reactive hypoglycemia (“low blood sugar attacks”). Acesulfame K apparently produced lung tumors, breast tumors, rare types of tumors of other organs (such as the thymus gland), several forms of leukemia and chronic respiratory disease in several rodent studies, even when less than maximum doses were given. According to the Center for Science in the Public Interest, it was petitioned on August 29, l988 for a stay of approval by the FDA because of “significant doubt” about its safety. – sweetpoison

I can’t recommend a product with these ingredients.

Yes, I should have asked to be certain about all the ingredients before purchasing, but we don’t always have time to check everything out. The web site for Oravive lead me to believe that NovaMin was the only ingredient in Oravive IMT Tooth Conditioner.€  The product page I visited describes NovaMin but doesn’t mention any other ingredients.

“Oravive IMT Tooth Conditioner uses natural mineral ions – calcium, phosphorus and sodium – to brighten, strengthen and desensitize your teeth. These are the same ions naturally found in saliva as the natural protection system for the mouth. You will see and feel healthy changes in your teeth and gums – and a more beautiful smile.”

Only after a call to the company did I figure out that clicking in a certain image on their web site lead to the ingredient list. UPDATE: 10/23/08 The FAQ now includes the ingredients.

I did purchase over $60 in single use packets from Oravive. I don’t care if it is sweet or not. It isn’t worth the risk of cancer. How about pure NovaMin, can I just buy that? I contacted the company and was informed that they don’t sell NovaMin alone, but they do provide it to researchers at no charge if they find the research interesting enough.€  I’d still like to make my own toothpaste with it.

108 thoughts on “My experience: Oravive with NovaMin

  1. SergeiRostov

    First, I have to ask why you didn’t look the ingredients up first, since they are all disclosed at Live and learn, I guess. 🙂

    Second, you’re most likely thinking of a different carbomer. “Carbomer” is also a generic name for synthetic polymers of acrylic acid used as emulsion stabilizers or thickening agents in pharmaceuticals and cosmetic products. They may be homopolymers of acrylic acid, crosslinked with an allyl ether pentaerythritol, allyl ether of sucrose, or allyl ether of propylene.
    It’s probably Carbomer 940, which passes straight through the digestive tract without being assimilated in any way.
    Third, I notice “apparently” and “possibly” in the Acesulfame quote. Seems like pretty weak verbiage (although maybe those words have a different meaning in research circles, I don’t know); I’d also like to see the data on increased risk, what dosages were given, etc…and if are there no more recent studies than those of 20 years or more ago.
    Fourth, I would be more concerned with the propylene glycol, which has been linked to kidney damage.
    Fifth, (regarding those last two points) I’m not much worried, since cancer and kidney disease is so easy
    to cure by natural means(…but Dr Schulze and his students -including me – have yet to find a natural tooth-remineralization protocol, so for now, it’ll have to do, followed by some cancer/kidney disease- preventative-and-curative protocols.
    Oh, and Sixth, if you’re that concerned about ingredients you could also try to find a local dentist who will give you Novamin (especially try holistic ones in your area). It may be expensive, bu tit sounds like it’s worth it.

  2. Mona

    Hello, I have been searching myself to find products that will help remineralize teeth. I have been using sensodyne pronamel and armand hammer age defying toothpaste. I have definitely seen a difference after a weeks use, I must admit I am also using a mineralization power and mouth rinse from it was not very expensive from my standards and a little bit goes a long way. I am still looking for other products so I hope you will do an update on this topic. My dentist also says that increasing your calcium intake would not hurt and eating green leafy vegatables is a good idea. I became interested in teeth remineralization because I breastfeed my son who is 23 months old and still nursing and I noticed white spots on his teeth, I looked further and I saw a few pits in his teeth, I was scared so I research homeremedies to rejuvenate teeth and I came across remineralization of teeth and I got all excited because I did not have a very good visit at the doctors office with my 23 month old and I do not want to subject him to the suggested procedures. I have been using the pastes above on my teeth and my sons teeth along with a waterpik to massage his gums and remove residue below the gumline, it take the place of flossing, I was not aware that it is important to floss for a child so young but it works for me and my child and my husband has started the regime as well. I do see a need to do more research on the toothpastes I am currently using. My next purchase is going to be the Dr. Collins Restore Remineralizing toothpaste. I do not care how much it costs as long as it repair the teeth without a procedure at the Dentist. Have you tried anything else? If you have please send me an email Take care

    1. Carol

      Good for you for continuing to nurse your child. I saw other comments that are obviously ignorant of the long term health benefits of nursing past two years of age so please ignore them. Human milk is loaded with antibodies and naturally fights bacteria, so your child’s teeth could be much worse if you were NOT nursing.

      You’re being a great mother. I just wanted you to know. The commenters below should do a little research instead of thinking tv sitcom jokes are facts. It’s embarrassing.

    2. Naomi

      Please do not take extra calcium. It does not do ANYTHING to help your bones or teeth (unless possibly when applied to the teeth topically). What it can do is elevate levels of calcium in the blood and create deposits in tissues and joints that later manifests as arthritic style inflammation. If you want to build your bones, take strontium not calcium. There has never been a study proving calcium builds strong bones. That is dairy industry social engineering at its finest. For confirmation of this information, google David Wolfe.

  3. TomyOS

    Are you crazy? You can breast feed your child till 18 years and change milk with beer immedately after that. Or you can go with him on first date for last breast feeding? I think that you want psichic dependance on child to you, and your child always be with you and no other. That’s sick! Sorry for your child.

  4. Brian

    I’ve been using novamin toothpaste for 2 years and I love it. My teeth have regrouped and have whitened 3x what they used to be. Cancer, fugetaboudit. White(er) teeth, I can smile again.

  5. Oravive user

    If the ingredients are the same as those in the prescription version of the toothpaste, SootheRX, one of the ingredients in question is
    Carbomer 934P, not carbamide peroxide. Though I can’t say I’m pleased about the presence of it or potassium acesulfame.

    This page discusses the “Toxicology of the Carbopol Polymers as a Class,” including 934P. this page discusses .

    SootheRX info page and ingredients:

  6. James

    I was doing some research on novamin and came across this page after that I researched amikacin on wikipedia. and It said this “Side effects of amikacin are similar to other aminoglycosides. Kidney damage and hearing loss are the most important effects. Because of this potential, blood levels of the drug and markers of kidney function (creatinine) may be monitored.” I don’t know If it is of any importance. maybe if it is an important ingredient.

  7. Randy

    The NovaMin you found is a completely different thing altogether — its a drug marketed for horses (has nothing to do with teeth or this product). The NovaMin (R) in Oravive has a chemical name Calcium Sodium Phosphosilicate and its a non-organic mix of calcium, sodium, phosphorus and silica (all of which naturally occur in teeth).

    In regards to Potassium Acesulfame its used in soft drinks. That doesn’t make it good, of course, but you would have to swallow the entire tube of toothpaste to get even close to what is in one can of diet soda. If you’re like most people you spit out 95% of the toothpaste, so ingestion is pretty trivial.

    1. andrew

      Could you please send me a little note when the all natural one is available.I am looking at angstrom minerals now .Got this info on with jini patel who said it remineralize her cavities but I still want to have other options as I have receding
      gums and also the dentin is also showing up in some of my teeth due to hard brushing for many years.

      Thank you.

      1. My Thoughts

        From what i am understanding about the angstrom minerals it simply just raises the pH in the mouth. You can easily do this by either rinsing out with water or better still just taking a bit of Baking Soda. To remineralize though you need to have calcium and phosphate aroudn when the pH is raised. The best way to do that without Novamin is simply to stimulate your saliva glands to secrete new saliva into the oral cavity. The easiest way is to chew sugar-free gum. I tend to use 100% xylitol gum and when i check my pH it spikes pretty high (9).

        Right now i’ve been testing Clinpro 5000 (1.1% NaF + Tri-Cal Phosphate), Dir Collins Restore (5% Novamin), Oravive Gel (5% Novamin), Varnish (5% NaF)…so far i dont see much difference that any of them provide. It’s possible i did notice that some of my teeth got a bit more opaque due to the novamin but besides that my teeth didnt get whiter nor did existing new white-spot lesions disappear caused by custom tray whitening (38% carbamide peroxide).

  8. Annette Bertolo

    I live in Toronto, Ontario, CANADA
    hopeing this can be ordered Direct and
    not on line. Also if this makes it to
    the stores, please let me know which stores
    would be selling this produce.

  9. Colin

    Novamin is patented an no one can else can manufacture or use it. In fact Novamin has been purchased by GSK and Oravive will be discontinued once they sell out of their remaining stock.

  10. Kevin

    I bought Oravive with NovaMin in Hong Kong many years ago – bottom line was that it worked, my teeth surface felt smoother and more even after a few brushes. Sadly i can’t buy this in Australia, and now Oravive is no longer made.

  11. Blake

    Hey! I hope people still use this site. I just had some microabrasian on my teeth (that is removing the top layer of the tooth to remove white spots without actually having to go so far as to need dental bonding or fillings)and the results were great but one of my teeth looks a little clear. Does NovaMin rebuild enamel and will make that white again? I keep getting the run around with what remineralization of the tooth is and I only want to know if the clear part of the tooth like mostly everyone has at the bottom of their teeth will regain color with the use of NovaMin? Thanks so much, I hope to hear from you soon!

    1. Ginger


      I’m a dental professional, and to my knowledge, you may find it challenging to find a topical product that will increase the opacity of the incisal (biting) edge of your teeth. If the surface is not too thin, you may get results with custommade trays filled with something like MI paste or NovaMin. Still, it wouldtake repeated applications, and possible the introduction of a mild dentist applied acid to creat a receptive surface.

      Reading some of the messages above has reminded me of how much misinformation is out there. I noted a lot of fear-based comments, and just plain ignorance diguised as fact. NovaMin is good stuff, I hope it re-appears in some readily available products.

      1. ewem

        I was searching for oravive to purchase and found this site. I did not know they stopped production. I have used it for years. I had read about Novamin being developed as a product for bone repair. That article mentioned because it is faster to get approval for toothpaste, Novamin was going to be marketed in toothpaste, and I located Oravive.
        1. Oravive rapidly changed the biting edges of my teeth from translucent to opaque. I used to be able to see the shadow of a finger placed behind my front teeth, along the lower edge
        2, Oravive quickly eliminated tooth sensitivity, to hot, cold and even touch
        3. I had tea and coffee stains on my rather yellowed teeth.
        Oravive returned my teeth to white by apparently overlaying these stains, not by bleaching. They look excellent, and they look like young teeth

        I am very disappointed Oravive has stopped production. They never mass marketed the product, which would have been a sensation as a desensitizer. Instead they tried to make it a specialty item to be sold by dentists. Now I am afraid I will not find a satisfactory replacement. Burt’s Bees product has botanicals, which I avoid. I just want novamin, some flavorings, and whatever fillers required to make it into a paste. Unfortunately a tube lasted a long long time and perhaps that was the problem.

        Oravive also used to be made in China, but switched to the USA. That does not mean the ingredients were not made in China. There is no way to verify if Dr Collins produces an American paste from Chinese compounds

        I am at a loss. Glaxo SK is a decent company, but are they going to mass market or make this product a hard-to-get? I assume their primary interest is R&D for bone repair

        Thanks for the info on this product. Sigh

  12. LadyHawk

    Effective April 30, 2010, Oravive ( has permanently closed its website!!! End of discussion. What’s that about???

    1. Lovethatsmile

      In May of this year (2010), Novamin (star ingredient for Oravive)was aquired by GlaxoSmithKline (makers of Sensodyne) for $135 million. My guess is that part of the aqusition included d/c of products associated with the original USBiomaterials Corp., and agreements with Randy Scott CEO and one of the founders of Oravive…and NO they are not from China. See Article below.

      1. 3BlindMice

        Wow… That GSK bought NovaMin really sucks. This probably means they will purposely prevent NovaMin products from being produced (at least outside denstist offices). This way, Sensodyne still controls the anti-sensitivity toothpaste market. As most here know, Sensodyne is not very effective, and GSK knows it.

        The one thing that gives me hope is the fact that Colgate Sensitive (the Exact same product as Sensodyne but cheaper and tastes better) is a really viable competitor to Sensodyne. If Colgate can pull consumers away from Sensodyne, GSK may pull out NovaMin products to lure them back. Even then, it will take awhile for them to develop a new product.

  13. GB

    I am also interested in novaMin. My son has 2 small cavaties on the bottom of his molars. Will or can this remineralize them?
    I contacted Burt’s Bees and they said their toothpaste has NovaMin. I wonder how much. Is it enough to do something or just for show. I know Cr. Collins has 5%.

  14. mo

    It’s my understanding that the discontinuation of availability of Oravive is that it is manufactured in China, which has a very questionable record of safety in their production practices, plus China still uses “forced” labor in some factories. However, the Novamin formula is reported to be available in 3M’s sensRx, Dr. Collins Restore and all Burt’s Bees toothpastes. The question raised above as to the percentage of Novamin in the Burts’ Bees toothpaste is worth investigating. While I generally like BBs products and recommend them, I am always concerned when the ingredients listed seem less than transparent as in this case. Perhaps, as has been mentioned, because Novamin is a proprietary product, BBs is using a similar hydroxyapetite product ‚Äî or perhaps they are indeed using Novamin (since when I did a search within their own web date base “Novamin” turned up all 6 toothpaste products) and question whether their natural products customer base might find a patented product “unnatural” and therefore did not want to list it outright. Either way, there does appear to be decent evidence that Novamin has a positive effect on strengthening and protecting certain portions of the teeth.

  15. LadyHawk

    My personal experience with Oravive is that it has whitened my teeth, after only about a week’s use, in a way that is clearly better than anything else I have ever tried. Furthermore, my teeth end up feeling squeaky clean each and every time I use it. The weird things about Burt’s Bees’ toothpaste are that: 1. The toothpaste itself is thick, syrupy, sticky and difficult to use; 2. Even the “Whitening” variety doesn’t whiten my teeth that well; 3. The ingredients lists for both the “Whitening” and the “Multi-care” toothpastes are identical, a fact that makes absolutely no sense. When I phoned Burt’s Bee and asked about the ingredients lists, the representative made light of the issue, claiming that just because the ingredients on the labels are the same, that doesn’t mean that the formulas are the same. Sic!

  16. Whatcha!

    Are the ingredients in a different order? If not then they’re lying through their teeth! (pun partially intended)

  17. LadyHawk

    Lying through their teeth. . . the ingredients on the Burt’s Bee’s Fluoride Free WHITENING toothpaste and Fluoride Free MULTICARE formula are 100% identical (i.e. same ingredients in the very same order). Perhaps this has something to do with the fact that Burt’s Bees was sold to CLOROX in 2003, and Burt got the short end of the deal. (See the ugly story at: I’ve decided to stick to another brand. Oravive was, in my opinion, the best; now I’m going to try Dr. Collin’s.

  18. BTW

    Did any of you who used Novamin and got teeth whitened in a week ever stop to think it is because this Oravive is too abrasive? Novamin is dangerously abrasive and should be taken off the market. And, there is no independent research that proves it prevents cavities, cures gingival inflammation or treats sensitivity. Emphasis is on “independent research”. All research out there is by people with a vested financial interest–this stuff should be discontinued by the FDA

    1. LadyHawk

      As posted by Xeno at the top o the page on October 11, 2008:

      “NovaMin releases high levels of Ca2+ and P5+ into the oral environment, along with Na+ that increases oral pH, creating the ideal conditions for rapid tooth remineralization. . . The NovaMin will release rapid and continuous deposition of a natural, crystalline hydroxyl-carbonate apatite (HCA) layer that is chemically and structurally the same as tooth mineral. No other man-made materials is known to directly lead to the formation of these crystals in the body.”

      I was of the opinion that it’s the remineralization process described above that is so effective at whitening. Yours is the first mention I hear that Novamin may be abrasive. In contrast to Orvive’s ingredients, those in professional whitening gels (i.e., carbamide peroxide, potassium nitrate and fluoride) sound lethal.

      My objective isn’t a Tom Cruise smile. In today’s appearance conscious society, I would simply like my teeth to look more white than yellow. It seems unfair that I walk around looking as if I have a “smoker’s smile” when I have never been a smoker.

      Perhaps it’s a matter of “pick your own poison.” In my sustained opinion, Oravive¬Æ was the absolute best. I have tried Burt’s Bees¬Æ, which is supposed to contain Novamin, and it’s a complete waste (grade D); I have tried Dr. Collins RESTORE¬Æ , which is supposed to contain Novamin, and it’s okay, but not great (grade B). Dr. Collins all White Whitening Toothpaste contains Xylitol, Peroxide and Sodium Monofluorophosphate and it comparable to Supersmile and Britesmile Whitening Toothpaste; thus it may not have any bearing on this discussion. Nevertheless, no other brands of toothpaste so far come close to Oravive¬Æ. Oravive¬Æ is/was in a class of it’s own — way ahead of the rest.

      1. Xeno Post author

        Thanks for the tips! I still have some oravive around. I’ve used 3% peroxide for whitening teeth. Also kills bacteria. Just put it on your toothbrush and brush with it. It is a weak acid that will remove stains. Don’t drink it and stop if it makes your mouth sore. Cheap and not so dangerous, since our bodies make it in small amounts. Read the label, and don’t use if it is more than 3% or says not for internal use.

    2. ewem

      It is not abrasion which whitened my teeth. Oravive returned the cutting edges (about 1/8 inch) from translucent to opaque. Truly opaque. I could see shadows through my front teeth before I used Oravive and it worked very quickly.

      As the opacity returned, it returned in patches. Some parts whiter and more opaque than others. Now my teeth are uniformly opaque

      I always brushed my teeth very lightly because of soft bleeding gums, but after using Oravive regularly, the reddened gum areas between teeth returned to normal pink, despite the fact I rarely floss. I know it had to be the exposure to something in the toothpaste which made the difference. Oravive removed my tooth sensitivity, which had grown very bad over many years. IMHO Oravive ie Novamin overlayed the tea and coffee stains on my front teeth. At the dentist, it took a ton of polishing to remove these stains which were back in a week. I dont even brush every day, and my teeth still stayed opaque and white

      I am depressed to say the least to find this product off the market.

      1. LadyHawk

        I have to agree with Ewem, and I will continue to keep in touch with this web site in case — by any miraculous turn of events — Oravive ever resurfaces (perhaps under a different name?). Meanwhile, I have taken Xeno’s advice and tried brushing with 3% hydrogen peroxide for whitening teeth. I have to admit that I am experiencing a slight improvement with the H3O2 — way better than any of the toothpastes (besides Oravive) that I have tried; and I have tried them ALL. The H3O2 even helps make my teeth feel impeccably clean; so that’s a plus. Thanks for this simple suggestion, Xeno! I’m surprised I never thought of it before.

      2. Linlee

        Since you had good results with Oravive, do you know what percentage of NovaMin was in it? Was it more than Dr. Collins Restore toothpaste?


      3. LadyHawk

        Linlee ~ Both Oravive and Dr Collins Restore claim to contain 5% NovaMin, but the practical difference between the two products is without compare. Oravive is/was in a class of its own. So far, I have not been able to find anything like it.

  19. ck

    I’ve used Dr Collin’s Restore Toothpaste for about 1.5 years. Novamin isn’t abrasive as far as I can tell, but the formula that Oravive created with it might.

    I will tell you one thing. It did help my sensitivity issues a ton. Not sure on the whitening, I didn’t notice any real difference there, as Dr Collin’s sells another toothpaste for whitening; I never bought that one.

    Unfortunately, since GSK bought Novamin, they are effectively off the market, and most likely, indefinitely.

    I hate it when company’s buy out a competitors superior products, just to SHELF them for good. Cisco loves doing this too. We probably won’t ever see a Novamin product again. I can’t believe this is happening too.

    I suppose I can’t blame the creators for selling out. $135 million bucks now is a lot of money, especially back in 2009. But who knows how many people like me will now suffer for decades because they cashed out?

    1. Xeno Post author

      There should be a law against buying and sitting on useful technology or cures. Imagine what would come out if there was.

      Movie idea: There are rumors… A network of underground cities, connected by tunnels. … inhabitants 50 years ahead of the surface technology, or 100 years … or 1000. The best stuff… energy, food, toys, weapons, heath care, all improved constantly by the brightest minds. They call us the Surfers– the surface dwellers–the shallow, superstitious, short term thinkers. We are their cattle. They scan us at airports, collect our DNA… They watch and orchestrate world events. The UFOs, the abductions, it’s them.

      Dr. Xe, a researcher in 2011, tracking the disappearance of a cure for dental cavities discovers much more: A genetically enhanced human race, highly organized, curious, careful and cunning. Occasionally compassionate?

      They are: The Underlords.

      Coming soon …

  20. Terrybeach

    I have some SEALED Oravive toothpaste that I would be willing to sell if anyone is interested. I just bought too much and will never go through it all. Just leave a comment and I will list it on Ebay.

    1. J

      I am very interested in buy oravive. Please contact me at



      (first letter of Goat) (i hate spam, sorry)

  21. Xeno Post author

    Just tried some more of my stored supply of the no longer produced Oravive. It definitely makes my teeth feel good and smooth after just one use. I think I can stretch mine out for a decade or so. I use it only when I have tooth sensitivity, which is rarely. When I use it, I am also using the Probiora formula mints (probiotic mints with good bacteria that fight off the cavity causing bacteria s. mutans.) I’ve spent about $60 on these mints, but this is less than I would spent on my copay for a dental visit and this way I don’t have to spend the time and money or get the shots and the drill. Get some pro-biotic mints before they suffer the same fate as Oravive with Novamin.

  22. LadyHawk

    After an intensive and lengthy search for toothpastes that could meet or challenge the effectiveness of Oravive, the article below by Dr. Gerald Judd became apparent and now has my attention. Judd promotes the concept of using bar soap instead of toothpaste because bar soap washed off the teeth in only one rinse where it take the glycerin in toothpaste as many as twenty-three (23) rinses to wash off:

    In his book ‚ÄúGood Teeth, Birth to Death‚Äú, Judd’s research reveals that toothpaste, and in particular glycerin, coats the teeth with a film that blocks calcium and phosphate entry and prevents re-mineralization. He says that lightly brushing with bar soap (not liquid soap) is the proper way to clean teeth and gums, that acids from foods are the real cause of cavities, and that soap takes oils and other items off the teeth effectively and cleans them perfectly. He also recommends that, in order to immediately rinse acids from the enamel, we rinse our mouths with a little water every time we eat.

    After about a week of brushing with plain ol’ Ivory bar soap, this is to report that Dr. Judd’s research may indeed make sense. My teeth appear to be as white now as they were with Oravive. Will wonders never cease?

    1. LadyHawk

      Dr. Judd’s protocol also includes taking about 1/5 teaspoon (1 gram) monosodium phosphate daily, dissolved in a glass of water. This, he says helps “reenamelize” the teeth and bones, which leach slightly with water over decades and lead to holey teeth and holey bones. Others, however, like Dr. Andrew Weil, point out that phosphorus is highly reactive and is never found in its free form it nature. Weil recommends getting phosphorus from diet alone as excessive intake of phosphorus (or phosphate supplements) may worsen conditions like heart disease, pancreatitis, rickets, osteomalacia (softening of bones), high blood pressure, and liver and kidney disease. Moreover, excessive phosphate intake can result in hyperphosphatemia (high blood phosphorus levels) which can lead to potentially serious electrolyte imbalances and even death. Yikes!

      Dr. Judd’s recommendation for unilaterial phosphate supplementation may thus be a bit too cavalier. I’m still brushing with bar soap — that seems harmless enough — but I’m steering clear of monosodium phosphate supplementation. It’s a great idea in relation to only the teeth or bones alone, perhaps, but it doesn’t seem healthful in terms of the entire system.

      1. tamsey

        this has been shown to be false… glycerin does no such thing
        actually, glycerin has antimicrobial properties and kills bacteria and is good for your teeth

  23. Former Oravive User

    Novamin is back, under the Sensodyne brand. Let’s hope this Sensodyne doesn’t also continue to contain the lovely ingredient that kills nerve endings, potassium nitrate.

    Also, given all the carcinogenic fragrances and other substances in soap, I doubt it’s a good thing to be putting your mouth.
    See the Environmental Working Group’s cosmetic safety database (which actually contains a wide range of personal care products).

    1. LadyHawk

      Wow! Thanks for the great news, Former Oravive User! Novamin in Sensodyne toothpaste sounds like a winner to me. I’m going to be on the lookout. Can’t wait!

    2. Violet

      It’s difficult to find an ingredients list for the new Sensodyne NUPRO. From what I’ve been able to gather, it does not appear to contain potassium nitrate, but it does contain fluoride. The only fluoride-free Sensodyne NUPRO product that I’ve been able to find is a “Prophylaxis Paste” that comes in cups. This, apparently, is a professional paste for polishing teeth in the (dental) chair.

      1. LadyHawk

        Perhaps we all ought to hound GlaxoSmithKline® (tel. 1-888-825-5249) abut producing a non-fluoride version of NUPRO with Novamin®.

      2. Yohiel

        Following LadyHawk’s advice, I recently contacted GSK and just received their odd reply:

        > We have received your e-mail message regarding Nupro toothpaste with Novamin.
        > This product is not available for sale in the United States.
        > We’re sorry to learn that you are not happy with our use of fluoride in our product.
        > Input from the users of our products is extremely important to us.
        > Please be assured that we will forward your feelings on the use of fluoride
        > to the appropriate individuals in our research & development area.
        > We appreciate your taking the time to contact us.
        > GlaxoSmithKline Consumer Healthcare

    3. LadyHawk

      I just contacted GSK on the Sensodyne® web site at, requesting them to please produce a no-fluoride version of their new Sensodyne® toothpaste with Novamin®, and including a link to an article on fluoride damage at . Their reply is below. Please get everybody you know to inundate these folks with requests for a no-fluoride Novamin® toothpaste. The squeaky wheel gets oil.

      We have received your e-mail on our Sensodyne® website.

      Your suggestions obviously represent careful thought and consideration, and we appreciate your taking the time to share them with us.

      GlaxoSmithKline Consumer Healthcare maintains a large Research and Development team whose mission is to formulate and test numerous product and packaging concepts for all of our brands. When a loyal customer offers a suggestion for improvement, you can be assured that we pass the information to that department for consideration. While we cannot promise that your ideas will result in a new formula, the information you provided allows us to view our efforts from the perspective of the customers who buy and use our products.


      GlaxoSmithKline Consumer Healthcare

    4. LadyHawk

      GlaxoSmithKline’s (GSK) may just be odd in general. Their latest offering appears to be a malaria trial vaccine that the company claims can cut the risk of clinical and severe malaria in children by 56 percent and 47 percent, respectively. But what GSK and the media are failing to report are the deadly side effects that may accompany the vaccine. OMG! And this is the company that bought out Oravive? Arg!

    1. Xeno Post author

      Wow, thanks Davis! The site is legit. I called and placed an order. They can sell it because they have some small travel sized tubes left, (the large ones are gone) but after their stock of a few hundred is gone, it’s all gone. The sales guy told me one travel tube would last about a week. Get some while you can! They have the fluoride free formula. I think they will sell out fast.

      The write up on the site says nothing rebuilds enamel, but this study at Louisiana State University’s School of Dentistry says Novamin does actually rebuild enamel:

      0396 Remineralizing Effects of a Bioactive Toothpaste
      N.K. SARKAR1, J. CHEUK1, R. SCHAFER1, K. LUONG1, and A. FALSTER2, 1Louisiana State University School of Dentistry, New Orleans, LA, 2Earth and Environmental Sciences, University of New Orleans, New Orleans, LA

      Aim: The aim was to study in vitro the efficacy of a bioactive toothpaste, Oravive (Oravive, Fl), in remineralizing decalcified dentin and enamel.

      Methods: Transverse sections from the coronal portions of extracted human molars (n=3) were final ground with 1200 grit SiC paper. For surface decalcification, the sections were etched with a 32% phosphoric acid gel and rinsed with water. Two etched sections were brushed for 1 min twice a day using Oravive toothpaste and a manual soft bristle toothbrush and rinsed with water. In between brushing, the sections were stored in a phosphate buffer saline (PBS) solution (pH = 7.2) at 37oC. The solution was replaced every day. After brushing for 10 d, the sections were cleaned ultrasonically in water, dried at 37oC, and examined by SEM and EDXA. The unbrushed etch section served as control.

      Results: Toothbrushed samples displayed 1) build up of a reaction layer covering the porous enamel prisms. Degree of coverage varied from place to place; 2) closure of open tubules, partially or completely, with reaction products growing from the peritubular dentinal area; and 3) infiltration of the intertubular matrix with numerous tiny (< 1µ) globules. All reaction products were similar chemically and contained mainly Ca, P, and O with small amounts (<2 wt%) of Na, Mg and Si. Presumably they are an HA-type mineral. Their formation is attributed to a dissolution-precipitation reaction involving Novamin, the bioactive calcium sodium silicophosphate component, of the paste.

      Conclusion: Oravive is highly effective in rebuilding demineralized dentin and enamel structures.

    2. LadyHawk

      Thanks Davis and Xeno! This is good news and bad news. Although a handful of one-week supplies in travel tubes is indeed better than nothing, the best of all worlds would be a sustainable source. It beats me why someone doesn’t simply reproduce the Oravive formula and be done with it! Till then becomes now. . .

      1. Novamin Hunter

        Yea i saw the prophy paste on nupro’s site too and was very interested but sadly they dont sell it to anyone who is not a dentist (i’m just a regular enthusiast) and the other problem for me…I’m Canadian and Nupro said they only sell in the US. Nupro in Canada does not carry this product. My best shot is to find a dental retailer in the US that ships to Canada which has this product. Not too many of those.

        If i could get that Nupro prophy paste that you mentioned ($242) i would prolly get it. Yes its a prophy paste but and i am no dentist but i am sure i could rub it on my teeth with my finger and get the 80% novamin working its magic 🙂 — with 700 doses that could last me 2 years (1 dose should be more than enough for my mouth).

        You know…not sure if you are up for it but if you are American and are able to get this product we could split this half/half and i would send my money to you (via PayPal or whichever) and you can just mail me my half of the prophy paste (350 cuplets of the 700) to Canada. If i could buy this thing at 242 i would right now but ah well.

        Anyway, if you are interested just contact me.

      2. LadyHawk

        Hi Hunter ~ Sorry for the delay! I only just now read your reply above and your offer. I’ll see what I can do. Last time I asked my dental hygienist about this, she was extremely unwilling. “Doctor would never let me do that,” she said about the dentist. But I have my own relationship with the dentist on another issue; so I’ll pass it by him the next time I’m in the dental chair. Thanks for the suggestion. I’ll see what I can do.

      3. LadyHawk

        Hunter ~ I finally got to speak to my dentist on this, and he too was discouraging. Although he didn’t take exception to the idea of using a finger to apply novamin prophly paste (“if you can get it”) to the teeth, he was not willing to purchase any amount of it for me in my behalf. I did, however, ask him about the wisdom of applying fine or extra fine diamond paste to the teeth for whitening, and he appeared more delighted about that possibility — especially since diamond paste is available to the general public and would not involve his office. Life!

    1. Violet

      I liked your idea about Sylc‚Ñ¢ Prophy Powder with Novamin and asked my dental hygienist about it. She said to stick with over-the -counter products. First of all, these pastes are too abrasive for everyday use; and secondly, the dentist would never allow her to give me, the patient, such a product for at-home use.

    2. Novamin Hunter

      I got information about osspray sylc…its kinda really expensive though…If you want feel free to email me and i will send you all the literature and pricing that was given to me.
      I was hoping to get this since it has 80% (or is it 100%?) NovaMin. It seems to be only sold by the manufacturer.

      Cheapest pricing: “Introductory 10-Single Packets (2g each)” = $49.99 — yikes! You can buy it in a bottle (2 bottles min) but its is $300+. Not sure why it costs so much seeing as how it is almost purely NovaMin.

      And just remember it is a powder so you would pretty much just rub it on your teeth and let your saliva flow do the work. My thinking was to apply Clinpro 5000 and use this as a aider in boosting the calc/phosphate levels even though Clinpro’s tri-calcium phosphate claims to be able to do that (i just dont buy 3M’s claims that clinpro can release the calc/phos more efficiently than novamin).

      Anyway, if anyone wants more info about osspray just email me at: forentuna [at] gmail dot com

    3. Novamin Hunter

      Hey Lady! Curious what is the difference between Oravive Revitalizing Tooth Paste and Oravive Revitalizing Tooth Gel? The ingredients seem identical (no clue on the inregdient quantity difference though).

      Is the oravive tooth paste just more abrasive than the oravive tooth gel, and so it wont matter (just personal taste — as long as it is Oravive, all is good)?

      1. LadyHawk

        Hi Hunter ~ My hunch is that “paste” and “gel” are just semantics. “Classic Tooth Revitalizing Paste” was probably Oravive’s first product. Then, when they developed Citrus Fresh, they decided to call it “Tooth Revitalizing Gel.” That’s my guess. Snag either one you can find. *Smiles*

  24. Novamin Hunter

    If anyone finds a solution to this NovaMin scarcity then please let me know.
    For the record anyone who is wondering the NovaMin levels for the available otc pastes are:

    Oravive (seems still avaialable at in 0.9 oz travel sizes @ $3.50) = 5% NovaMin
    Dr Collins Restore (4 oz) = 5% NovaMin
    Osspray Sylc (price varies but low of $49.99 for 20g total) = 80%-100% NovaMin

    Right now i am going to be using ClinPro 5000 from 3M which has a competing brand to NovaMin called Tri-Calcium Phosphate. They claim it is more efficient in delivery of calcium and phosphate which are the key ingredients for NovaMin but i have my doubts which is why i am looking to supplement my ClinPro usage with a NovaMin rub after each brushing.

    Ideally i want the highest % NovaMin for the cheapest cost but so far there isnt much selection choice. The Sylc line is way too expensive so i wish i knew if it would work better at such a high concentration. I have white spot lesions and NovaMin is actually able to fix that over time.

    1. LadyHawk

      Thanks for all the invaluable research, Hunter. 5% Novamin® or not, the practical contrast between Oravive and Dr. Collins as you may know is like night and day. Oravive is leagues ahead.

      Perhaps you too would like to contact GSK, asking them to please produce a no-fluoride version of their new Sensodyne® NuPro toothpast with Novamin®. I emailed them at, requested that they produce a no-fluoride version of their new Sensodyne® toothpaste with Novamin®, and included a link to an article on fluoride toxicity at . Their reply is below. Please contact them and get everybody you know to inundate them with requests for a no-fluoride Novamin® toothpaste. They are also available by phone at 1-888-825-5249.
      We have received your e-mail on our Sensodyne® website.

      Your suggestions obviously represent careful thought and consideration, and we appreciate your taking the time to share them with us.

      GlaxoSmithKline Consumer Healthcare maintains a large Research and Development team whose mission is to formulate and test numerous product and packaging concepts for all of our brands. When a loyal customer offers a suggestion for improvement, you can be assured that we pass the information to that department for consideration. While we cannot promise that your ideas will result in a new formula, the information you provided allows us to view our efforts from the perspective of the customers who buy and use our products.


      GlaxoSmithKline Consumer Healthcare


    Trying to find the CAS # for Novamin, calcium sodium phosphosilicate.

    William C. Domb, DMD

    1. LadyHawk

      Hi Greg ~ This sounded like great information; so I contacted Schott, the makers of Vitryxx®, and asked if Is Vitryxx® uses a similar calcium sodium phosphosilicate technology to that used in NovaMin®.

      Where the Vitryxx® product description sheet states, “The sum of all heavy metal impurities, namely lead (Pb), mercury (Hg),bismuth (Bi), arsenic (As), antimony (Sb), tin (Sn), cadmium (Cd), silver(Ag) and copper (Cu) is less than 50 ppm.(Pb, Hg, Bi, As, Sb, Sn, Cd, Ag, Cu) < 50 ppm," I also asked if there have been any tests to indicate whether these metal levels pose a toxicity concern if taken internally (as a residual of tooth-polishing) in these concentrations?

      Susanne Kessler, Manager Technical Sales Product Division Glass at Schott wrote back:

      "due to the existing patent situation we are in no way free to offer you any glass similar to NovaMin® for any oral application. Please be aware that the NovaMin® technology is tightly patented and there is no freedom to operate without a valid licencing agreement with GlaxoSmithKline."


  26. Novamin Hunter

    Curious what is the difference between Oravive Revitalizing Tooth Paste and Oravive Revitalizing Tooth Gel? The ingredients seem identical (no clue on the inregdient quantity difference though).

    Is the oravive tooth paste just more abrasive than the oravive tooth gel, and so it wont matter (just personal taste — as long as it is Oravive, all is good)?

    1. LadyHawk

      Hi Hunter ~ This becomes a rather mute point since, as we know, Oravive is no longer available in either gel or paste form. Nevertheless, in checking my emergency stash, I discovered that my box of “Citrus Fresh” is called “Tooth Revitalizing Gel,” and my box of “Classic” is called “Tooth Revitalizing Paste.” Having used only the Citrus Fresh so far, I have no idea if the product behind the seal in the Classic tube is any different except for name and flavor. My hunch is that it isn’t.

  27. Jason

    Just thought I’d post this, in Canada my dentist sells a product called “X-Pur Tooth Revitalizing Paste” which has 5% Novamin in it. According to the site for the manufacturer (a company called Oral Science) its available in pharmacies as well (they appear to be based in Quebec as the list of pharmacies is mostly local quebec chains). I’ve just started using it, will see how it works but so far no issues

    1. LadyHawk

      Wow Jason! ‘Great find! Thanks for sharing! I, for one, will do my best to track this into the US is at all possible. *Smiles*

  28. Former Oravive User

    I noticed that this sheet states, “The sum of all heavy metal impurities, namely lead (Pb), mercury (Hg),bismuth (Bi), arsenic (As), antimony (Sb), tin (Sn), cadmium (Cd), silver(Ag) and copper (Cu) is less than 50 ppm.
    (Pb, Hg, Bi, As, Sb, Sn, Cd, Ag, Cu) < 50 ppm"

    Does anyone know if any of these metals pose issues at these concentrations? (If in fact the Vitryxx is the calcium sodium phosphosilicate used?) And if similar heavy metal impurities would exist for "regular" toothpaste?

    1. LadyHawk

      Wow User! What a terrific find! You have indeed been doing your homework. My guess is that the best people to answer this question are the folks at Schott. I’m going to email right now to see what they have to say. I’ll let you know as soon as I have a reply.

    2. LadyHawk

      Just heard back from Schott. Here’s a copy of their email:

      Dear (LadyHawk),

      due to the existing patent situation we are in no way free to offer you any glass similar to NovaMin® for any oral application. Please be aware that the NovaMin® technology is tightly patented and there is no freedom to operate without a valid licencing agreement with GlaxoSmithKline.

      Thank you for your understanding.
      Best Regards

      Susanne Kessler
      Manager Technical Sales Product Division Glass

      phone: +49 (0)871/826 709 Fax–Nr.: +49 (0) 3641/28889 096

      1. Jay

        Despite her insistence, I strongly suspect that Vitryxx and Novamin are almost identical products with different branding. All products termed “bioactive glass” contain the same major constituents, and all of them release calcium and phosphate when dissolved in water (or saliva). That combination will crystallize as hydroxyapatite (or related compounds) when the pH is alkaline.

        The heavy metal impurities level of less than 50 ppm is inconsequential, though ideally you’d want to know the individual levels of the significantly common toxic metals – lead, arsenic, cadmium.

  29. Violet

    This is not a Novamin product, but I recently discovered a tooth powder (“Eco-Dent ExtraBrite”) that is the best I’ve found since Oravive. It whitens my teeth, and — just as importantly — it makes my mouth and teeth feel fresh, tingly and squeaky clean the way Oravive used to. I’m on my second tube of the stuff, and I keep my last tube of Oravive Citrus Fresh on the top shelf of the medicine cabinet for special occasions. Compared to Burt’s Bees, Dr. Collins’ and several other supposedly Novamin products, this one (“Eco-Dent ExtraBrite”) is my current favorite choice. Read more about it at and get $5.00 off your first-time iHerb order by using Coupon Code OPI185 at checkout.

    1. Me

      I recall my brother getting this way back and from my studies i notice it is merely an abrasion paste and oddly it even includes an acid which goes against the remineralization process. Its definitely all natural but i personally feel it does nothing special but relly on friction ot whiten teeth. And for remineralization it just relies on your own saliva mineral content. It would be more efficient to use a fluroide abrasion whitener instead since at least fluoride makes a harder enamel.

      1. Xeno Post author

        I don’t think we are talking about the same product. Novamin in Oravive does the remineralization and I’m looking at the ingredients now … I see no type of acid listed. It does have silica for abrasion and titanium dioxide for whitening…

        1. Me

          Hi Xeno…actually i think you arent noticing the msg i am responding to… i was respnding to someone talking about the “Eco-Dent ExtraBrite” product. Eco-Dent is nothing more than an abrassion paste (no remineralization stuff inside). So you are indeed correct about Novamin and Oravive they are true remineralizers. I’ve actually used Oravive Gel and a few other pastes with Novamin. I like them. However, for “Eco-Dent” its more a YMMV since it does nothing to remineralize except for stripping enamel to give you the illusion of whitening (well technically its more like scrubbing off the surface extrinsic stains but i personally find it lacking — and worst of all it includes a form of acid to help soften the surface of the tooth so the abrasion scrubbing can be more effective…yikes!).

          I was trying to get a 10% Novamin paste but failed in my attempts. Max i’ve ever found is 5%. I’ve read a bunch of studies and the best is the careful package ones that include both fluroide and Novamin which is tough to find since a few i’ve found dont realize that Novamin with its calcium when it comes into contact with Fluroide with actually become a compound (CaFl) which is much tougher to break down in your mouth which the two as separate ions (alongside phosporoush) are necessary to begin the remineralization process. That is why you rarely see fluroide-novamin pastes and the ones that do have them forget this simple chemistry problem.

          If i recall Novamin was bought out by GKS who market a product called Sensodyne. Here in Canada Novamin has never been available so Novamin has only been avail mostly in the states and some other countries around the world (e.g. UK) but the remaining supplies out there are the only batch of Novamin left in existence. GKS shelved Novamin because it inadvertently comeptes directly with their Sesodyne line by way of being a better solution to sensitive teeth. Currently, to solve sensitive teeth you’d use paste with potassium nitrate. That substance only numbs the nerve to give you the feeling of relief by using the paste. It does not solve the problem but makes you a life time customer for GKS’s line of pastes. Novamin on the other hands does something different. It flows into the pores of those sensitive teeth regions and actually “repairs” them. And so in the long term Novamin solves the problem of senstive teeth…not a good business strategy which is why they had to buy it out and shelf it. It’s very much like someone who ever figures out the cure for cancer–the smart thing would be to never let the public know about it nor get access to it…better to sell them pills to keep the cancer under control and have a life time customer. I know if i owned a pharaceutical company i would do the very same thing. So for GKS i salute them in their business acumen. For the rest of us i say to them: F**kers!

      2. Xeno

        Sorry, you are correct. I couldn’t see that in my WordPress app for my iPhone. Thanks for the correction.

  30. LadyHawk

    Thanks for this info Violet! Based on your recommendation, I have tried Eco Dent ExtraBrite and, like you, i find it leaves my mouth feeling fresh and squeaky clean. The powder is somewhat awkward to use at first until you get used to it, but the results are worth the effort. Thanks also for the discount coupon code. With free shipping on orders over $20; the $5,00 off was like getting the tooth powder for FREE just by throwing in a couple of additional items. Until Oravive is back on the market (“Oh please! May it be soon!”) this tooth powder is a definite runner up. Sincere appreciations!

  31. LadyHawk

    Chances are GlaxoSmithKline (GSK), the owner of Novamin®, is not going to be a Good Samaritan and use Novamin® to benefit people. At the link below, NaturalNews reports that GSK just admitted to $3 billion in criminal fraud, the biggest health care fraud case in history.

    GSK pleaded guilty to bribing physicians to push potentially dangerous drugs in exchange for gifts, cash and lucrative speaking engagements. The company also admitted to distributing misleading info regarding at least three of its products: Paxil® (which has been linked to teen suicides), Avandia® (which has been found to increased risk of heart attacks in diabetics), and Wellbrutin® (which GSK has been recommending for a laundry list of uses, none of which was approved).

    Perhaps, in order to pay the $3 billion in penalties, GSK will now sell Novamin¬Æ to a more philanthropic owner. Stranger things have happened. Keep those prayers and positive vibes comin’.

    Learn more:

  32. matheuu

    Hi Guys,
    Just been reading your thread. Sweet, thanks all.

    On a side note.. I did a job down in Melbourne Australia last year.. at a University there…. I was working throughout the chemistry department labs and bumped into a friendly chemist there who was working… had been working for years to put Novamin into a chewing gum.

    Im not sure if the chemistry or legalities were holding him back.. but he seemed a little frustrated when talking about it.. although I must say he was extremely excited and hopefull he could get an easy to use product out and about that would a lot of people all around the world…

    Anyone heard anything more???

    1. LadyHawk

      Hi Matheuu ~ The only gum I’ve been able to find that comes close to anything like this is Trident Xtra Care¬Æ with Recaldent¬Æ. Recaldent¬Æ is said to deliver superior tooth strengthening power via “a unique form of calcium, which is absorbed right into the tooth, strengthening areas attacked by plaque acids.”

      Technically casein phosphopeptides – amorphous calcium phosphate (CPP-ACP), Recaldent¬Æ is derived from casein, a part of the protein found in cow’s milk. It s said to help strengthen and rebuild tooth enamel by delivering calcium and phosphate to the teeth in a way that penetrates the enamel and remineralizes areas that have been affected by plaque bacteria.

      What do you think? Does anyone have an educated opinion? How does CPP-ACP’s reported action stack up in relation to that of calcium sodium phosphosilicate (i.e., bioactive glass aka: Novamin)?

  33. Andy

    In the UK GSK are now selling Sensodyne Repair and Protect – powered by Novamin. So looks like not shelved but incorporated into their product line.

  34. Nicola

    I bought the Sensodyne Repair & Protect yesterday, it doesnt have potassium nitrate in it! I would be very surprised if GSK produced anything that would help people…. but fingers crossed. There is another product with Novamin in it Ive been told about but I havent looked into it yet, its called sensishield. I dont know about the ingredients in toothpastes, so if any of you woth knowledge could have a look at it and post about what they think that would be great. Here is the link to sensishield –

    1. LadyHawk

      I’m with you, Nicola: GSK is self-serving and not to be trusted. Below, however, are the ingredients in “Sensishield” which is said to be powered by Novamin:

      Glycerin, silica, PEG 400, calcium sodium phosphosilicate, sodium lauryl sulfate, titanium dioxide (CI 77891), aroma, carbomer, potassium acesulfame, limonene.

      At the moment, Sensishield appears to be out-of-stock across the board. I’ve checked, and Nada! Zilch! Finito! Unavailable! Most likely the handiwork of GSK behind the scenes! Bah!

  35. LadyHawk

    I have been reading about Diatomaceous Earth (DE) and recently tried it as a tooth powder. From the very first brushing, my teeth turned out a remarkable one or two shades whiter in color.

    DE is a natural occurring siliceous sedimentary mineral compound from the microscopic skeletal remains of unicellular algae-like plants called diatoms. The diatoms have a hard shell made of non-crystalline silica, which does not decompose in the dried lake and ocean beds where their fossils are found.

    Once mined, DE is ground and screened to various grades. Crushed to a fine powder and observed through a microscope, DE particles resemble bits of crushed glass. The powder provides a broad spectrum of naturally occurring chelated minerals, including the following:

    Silicon Dioxide (SiO2) – 83.7%,
    Aluminium Oxide (A12O3) – 5.6%,
    Iron Oxide (Fe2O3) – 2.3%
    Calcium Oxide (CaO) – 0.4%,
    Magnesium Oxide (MgO) – 0.3%,
    Other Oxides – 1.9%.

    Analysis of other elements:

    Copper – 2ppm,
    Strontium – 100ppm,
    Titanium – 1800ppm,
    Manganese – 200ppm.
    Sodium – 2000ppm,
    Vanadium – 500ppm,
    Boron – 50ppm,
    Zirconium – 220ppm.

    Although a few articles mention lightly the concerns of DE being abrasive to tooth enamel when used regularly, most speak of the remedial and remineralizing effect of so much silica on teeth, gums and bone structure.

    Oh wise sages of the Oravive/Novamin blog, what say you? Might Diatomaceous Earth be the organic precursor after which Novamin (aka: “bio-available glass”) was fashioned? Moreover, does the remineralizing effect of using DE as a tooth powder override its obvious abrasiveness, or does the abrasion trump its remineralization potential?

    1. Xeno Post author

      Interesting. I’d probably avoid it due to the aluminum, vanadium and strontium but research is needed to determine if ionic calcium etc. is delivered to teeth with DE.

      Here’s a review of how Novamin works. Would DE do this?

      NovaMin is the brand name of a particulate bioactive glass that is used in dental care products for remineralisation of teeth. It was developed and patented by NovaMin Technology, Inc.. The active ingredient is the inorganic chemical calcium sodium phosphosilicate.[1]

      NovaMin delivers silica and ionic calcium, phosphorus, and sodium, which are necessary for bone and tooth mineralization.

      How it works

      NovaMin particles bind to the tooth surface and, when the particle comes in contact with saliva and water, reacts with the water to release calcium and phosphate ions. These ions are protected by glass particles so that they can be delivered to specific locations rather than as a liquid solution. Sodium ions in the particles exchange with hydrogen cations, which allows the calcium and phosphate ions to be released. A calcium phosphate layer then forms and crystallizes as hydroxylapatite, a form of hard and strong mineral in teeth. The physical occlusion of dentinal tubules results from both the hydroxylapatite layer and the residual NovaMin particles.[1][2]

      The chemical reaction that leads to hydroxylapatite is:

      5Ca2+ + 3PO43– + OH– → Ca5(PO4)3(OH)

      1. LadyHawk

        > research is needed to determine if ionic calcium etc.
        > is delivered to teeth with DE.

        Yes, indeed!

        A Google search for “diatomaceous earth hydroxylapatite” produces several links to at least one study of the adhesion and proliferation of osteoblast-like cells re: Silicon-hydroxyapatite bioactive coatings (Si-HA) from diatomaceous earth and silica. A 6-page report on this matter is viewable at

        As an abstract, the following is from

        The aim of this study consisted on investigating the influence of silicon substituted hydroxyapatite (Si-HA) coatings over the human osteoblast-like cell line (SaOS-2) behaviour. Diatomaceous earth and silica, together with commercial hydroxyapatite were respectively the silicon and HA sources used to produce the Si-HA coatings. HA coatings with 0 wt% of silicon were used as control of the experiment. Pulsed laser deposition (PLD) was the selected technique to deposit the coatings. The Si-HA thin films were characterized by Fourier Transformed Infrared Spectroscopy (FTIR) demonstrating the efficient transfer of Si to the HA structure. The in vitro cell culture was established to assess the cell attachment, proliferation and osteoblastic activity respectively by, Scanning Electron Microscopy (SEM), DNA and alkaline phosphatase (ALP) quantification. The SEM analysis demonstrated a similar adhesion behaviour of the cells on the tested materials and the maintenance of the typical osteoblastic morphology along the time of culture. The Si-HA coatings did not evidence any type of cytotoxic behaviour when compared with HA coatings. Moreover, both the proliferation rate and osteoblastic activity results showed a slightly better performance on the Si-HA coatings from diatoms than on the Si-HA from silica.

        Are we getting any warmer?

  36. Violet

    With reference all the way back to Ginger’s mention of MI Paste on November 6, 2010 and to LadyHawk’s question about Recaldent‚Ñ¢on November 21, 2012, this is to mention that my dental hygienist happened to recommend MI Paste to me today. MI Paste contains the active ingredient Recaldent‚Ñ¢ (a special milk derived phosphopeptide that binds calcium and phosphate to tooth surfaces). It uses calcium and phosphate to replenish and strengthen the minerals in teeth.

    It’s been a number of years since this blog has seen much activity, but does anyone out there happen to know how Recaldent‚Ñ¢’s calcium/phosphate chemistry stacks up to the calcium sodium phosphosilicate in Novamin¬Æ? Thanks!

    1. Xeno

      I haven’t seen data comparing clinical efficacy but I tried Recaldent lozenges and they gave me a stomach ache. I think Novamin would win in a remineralizing shoot out, but I can’t prove that. PS, Ask for the MI paste without fluoride. My dentist says there is one.

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